Molecular and antigenic characterisation of ribosomal phosphoprotein P0 from Babesia bovis

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Molecular and antigenic characterisation of ribosomal phosphoprotein P0 from Babesia bovis.

Babesia bovis is a tick-borne pathogen that remains an important constraint for the development of cattle industries in tropical and subtropical regions of the world. Effective control can be achieved by vaccination with live attenuated phenotypes of the parasite. However, these phenotypes have a number of drawbacks, which justifies the search for new, more efficient immunogens based mainly on ...

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Nucleotide sequence of a rice acidic ribosomal phosphoprotein P0 cDNA.

The eukaryotic 38-kD acidic ribosomal protein PO is localized to the stalk of the 60s ribosomal subunit, forming a pentameric complex with dimers of 13-kD acidic ribosomal proteins P1 and P2 (Rich and Steitz, 1987). P1 (P2) and PO are analogous to Escherichia coli ribosomal protein L7/L12, and L10, respectively, and are thought to have the same functions as their prokaryotic counterparts, i.e. ...

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Identification, expression and characterisation of a Babesia bovis hexose transporter

Babesia are tick-transmitted haemoprotozoan parasites that infect cattle, with an estimated 500 million at risk worldwide. Here, two predicted hexose transporters (BboHT1 and 2) have been identified within the Babesia bovis genome. BboHT1, having 40% and 47% amino acid sequence similarity compared with the human (GLUT1) and Plasmodium falciparum (PfHT) hexose transporters, respectively, is the ...

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Cloning and characterization of the gene encoding ribosomal P0 phosphoprotein from Neurospora crassa.

A gene for ribosomal protein P0 that belongs to the family of ribosomal P proteins was isolated from a Neurospora crassa cDNA library, using polyclonal antibodies against recombinant P0 protein from Saccharomyces cerevisiae. This is the first gene for ribosomal P0 protein to be cloned from filamentous fungi. The derived P0 protein sequence has a strong homology to other eukaryotic P0 proteins; ...

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 2009

ISSN: 0074-0276

DOI: 10.1590/s0074-02762009000700010