Modulation of IL-27 in adipocytes during inflammatory stress
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چکیده
منابع مشابه
Interleukin (IL)-6 Inhibits IL-27- and IL-30-Mediated Inflammatory Responses in Human Monocytes
Interleukin (IL)-30, the IL-27p28 subunit of the heterodimeric cytokine IL-27, acts as an antagonist of IL-27 and IL-6 signaling in murine cells via glycoprotein 130 (gp130) receptor and additional binding partners. Thus far, functions of IL-30 have not been fully elucidated in human cells. We demonstrate that like IL-27, IL-30 upregulated TLR4 expression to enhance lipopolysaccharide-induced T...
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ژورنال
عنوان ژورنال: Obesity
سال: 2015
ISSN: 1930-7381
DOI: 10.1002/oby.21351