Modulation of Cyp450, ALS1 and COX-2 signaling pathways induced by Candida albicans infection via novel antifungal agents
نویسندگان
چکیده
منابع مشابه
Resistance of Candida albicans biofilms to antifungal agents in vitro.
Biofilms formed by Candida albicans on small discs of catheter material were resistant to the action of five clinically important antifungal agents as determined by [3H]leucine incorporation and tetrazolium reduction assays. Fluconazole showed the greatest activity, and amphotericin B showed the least activity against biofilm cells. These findings were confirmed by scanning electron microscopy ...
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In recent decades, the incidence of invasive fungal infections has increased notably. Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on human mucosal surfaces, can cause fungal infections, especially in immunocompromised and high-risk surgical patients. In addition, the wide use of antifungal agents has likely contributed to resistance of C. albicans to tradi...
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ژورنال
عنوان ژورنال: Saudi Pharmaceutical Journal
سال: 2018
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2018.01.007