Modulation of adipocyte lipogenesis by octanoate: involvement of reactive oxygen species
نویسندگان
چکیده
منابع مشابه
Modulation of adipocyte lipogenesis by octanoate: involvement of reactive oxygen species
BACKGROUND Octanoate is a medium-chain fatty acid (MCFA) that is rich in milk and tropical dietary lipids. It also accounts for 70% of the fatty acids in commercial medium chain triglycerides (MCT). Use of MCT for weight control tracks back to early 1950s and is highlighted by recent clinical trials. The molecular mechanisms of the weight reduction effect remain not completely understood. The f...
متن کاملAdipocyte Reactive Oxygen Species Production
SUN, XIAOCUN AND MICHAEL B. ZEMEL. 1 ,25Dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production. Obesity. 2007;15:1944–1953. Objective: We have previously shown 1 ,25-dihydroxyvitamin D3 [1 ,25-(OH)2D3] to inhibit mitochondrial uncoupling protein 2 (UCP2) expression in adipocytes and that in vivo suppression of calcitriol levels with calcium-rich diets increases UCP2 expr...
متن کاملHypoxic relaxation of penile arteries: involvement of endothelial nitric oxide and modulation by reactive oxygen species.
Although obesity-related cardiovascular disease and hypoxia are associated with erectile dysfunction, little is known about the direct effects of hypoxia on penile arteries. In the present study, the effects of acute hypoxia (Po(2) = approximately 10 Torr, 20 min) were investigated in isolated penile arteries to determine the influence of endothelium removal, nitric oxide (NO) synthase (NOS), c...
متن کاملInvolvement of glutamate and reactive oxygen species in methylmercury neurotoxicity.
This review addresses the mechanisms of methylmercury (MeHg)-induced neurotoxicity, specifically examining the role of oxidative stress in mediating neuronal damage. A number of critical findings point to a central role for astrocytes in mediating MeHg-induced neurotoxicity as evidenced by the following observations: a) MeHg preferentially accumulates in astrocytes; b) MeHg specifically inhibit...
متن کاملO 22: Reactive Oxygen Species and Epilepsy
Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nutrition & Metabolism
سال: 2006
ISSN: 1743-7075
DOI: 10.1186/1743-7075-3-30