Modification of gellan gum with nanocrystalline hydroxyapatite facilitates cell expansion and spontaneous osteogenesis
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چکیده
منابع مشابه
Gellan gum microgel-reinforced cell-laden gelatin hydrogels.
The relatively weak mechanical properties of hydrogels remain a major drawback for their application as load-bearing tissue scaffolds. Previously, we developed cell-laden double-network (DN) hydrogels that were composed of photocrosslinkable gellan gum (GG) and gelatin. Further research into the materials as tissue scaffolds determined that the strength of the DN hydrogels decreased when they w...
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Gellan gum is a hydrogel-forming polysaccharide when combined with monovalent or divalent cations such as sodium, magnesium, potassium or calcium. Commercially, gellan gums are sold with trace amounts of these cations, which have been proven to affect the gelation and mechanical properties of the resultant hydrogels. A new method based on impedance analysis for determining the gel transition te...
متن کاملModified Gellan Gum hydrogels with tunable physical and mechanical properties.
Gellan Gum (GG) has been recently proposed for tissue engineering applications. GG hydrogels are produced by physical crosslinking methods induced by temperature variation or by the presence of divalent cations. However, physical crosslinking methods may yield hydrogels that become weaker in physiological conditions due to the exchange of divalent cations by monovalent ones. Hence, this work pr...
متن کاملElectrically conducting PEDOT:PSS - gellan gum hydrogels
Hydrogels consisting of the conducting polymer PEDOT:PSS and the biopolymer gellan gum (GG) were characterized using electrical, mechanical and rheological methods. Compression testing and rheological analysis showed that the gels weakened with increasing PEDOT:PSS content. In contrast, the increasing PEDOT:PSS content resulted in an increasing electrical conductivity. Disciplines Medicine and ...
متن کاملPreparation and Evaluation of Soft Gellan Gum Gel Containing Paracetamol
The objective of this study was to develop soft paracetamol gel using gellan gum as a gelling agent and sodium citrate as a source of cation. Different batches were prepared using three different concentrations of gellan gum (0.1, 0.3, and 0.5%), each with two different sodium citrate concentrations (0.3 and 0.5%). The consistency of the paracetamol gel was dependent on the concentration of gel...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 2016
ISSN: 0006-3592
DOI: 10.1002/bit.25915