Moderate-to-severe Vipera berus envenoming requiring ViperaTAb antivenom therapy in the UK
نویسندگان
چکیده
منابع مشابه
Immunological Cross-Reactivity and Neutralisation of European Viper Venoms with the Monospecific Vipera berus Antivenom ViperaTAb
Medically important cases of snakebite in Europe are predominately caused by European vipers of the genus Vipera. The mainstay of snakebite therapy is polyclonal antibody therapy, referred to as antivenom. Here we investigate the capability of the monospecific V. berus antivenom, ViperaTAb®, to cross-react with, and neutralise lethality induced by, a variety of European vipers. Using ELISA and ...
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CONTEXT In clinical practice it is difficult to differentiate between V. berus and V. ammodytes venomous bites. In the past this was not a concern, but due to the current shortage in Viperfav™ and European viper venom antiserum availability, V. a. ammodytes venomous bites have recently been treated with ViperaTAb®, which is a pharmaceutical formulation containing a monospecific ovine Fab fragme...
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Snake venom is a rich source of peptides and proteins with a wide range of actions. Many of the venom components are currently being tested for their usefulness in the treatment of many diseases ranging from neurological and cardiovascular to cancer. It is also important to constantly search for new proteins and peptides with properties not yet described. The venom of Vipera berus berus has hem...
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Vipera berus bites lead to a variety of clinical manifestations. Local swelling, coagulopathy, nephrotoxicity, cardiac effects and myotoxicity are known to be associated with envenoming by a viper bite. Although a variety of clinical manifestations have been reported in viper bite cases, anaphylactic reactions and liver injury events have not been described. We report a unique case of an anaphy...
متن کاملHospital contacts after bite by the European adder (Vipera berus).
INTRODUCTION Bites by the European adder, Vipera berus, may cause significant morbidity in bite victims, but this can be reduced through adequate treatment. Since the previous Danish study, a new treatment and a severity grading has been taken into use. The aims of this study were to review clinical cases after a bite from V. berus in The North Denmark Region and to evaluate the treatment given...
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ژورنال
عنوان ژورنال: Clinical Toxicology
سال: 2021
ISSN: 1556-3650,1556-9519
DOI: 10.1080/15563650.2021.1891245