Modelling Down syndrome
نویسندگان
چکیده
منابع مشابه
Modelling Down syndrome.
Animal models are extensively used in genetics, neuroscience and biomedical research. Recent studies illustrate the usefulness and the challenges of research utilising genetically engineered mice to explore the developmental biology of Down syndrome. These studies highlight many of the issues at the centre of what we understand about Down syndrome, and may one day point to useful ways to improv...
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Down syndrome is characterized by a series of minor anomalies that eachoccurwitha frequencyofabout50– 80% and will not, therefore, be present in all persons with Down syndrome. Conversely, it will be very rare for any single individual with Down syndrome to have all these anomalies, which include brachycephaly, oblique (upslanting) palpebral fissures, epicanthic folds, Brushfield spots, folded ...
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ژورنال
عنوان ژورنال: Down Syndrome Research and Practice
سال: 2008
ISSN: 0968-7912,1753-7606
DOI: 10.3104/updates.2054