Modeling payback from research into the efficacy of left-ventricular assist devices as destination therapy
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منابع مشابه
Modeling payback from research into the efficacy of left-ventricular assist devices as destination therapy.
OBJECTIVES Ongoing developments in design have improved the outlook for left-ventricular assist device (LVAD) implantation as a therapy in end-stage heart failure. Nevertheless, early cost-effectiveness assessments, based on first-generation devices, have not been encouraging. Against this background, we set out (i) to examine the survival benefit that LVADs would need to generate before they c...
متن کاملLeft ventricular assist devices as destination therapy.
Although an estimated 16,500 Americans annually could benefit from a heart transplant, in 1999 only 2184 heart transplants were performed in the United States. These statistics emphasize the severity of the shortage of available hearts for transplantation. Circulatory support provided by an implantable Left Ventricular Assist Device (LVAD) that meets Food and Drug Administration approval as des...
متن کاملDying With a Left Ventricular Assist Device as Destination Therapy.
BACKGROUND Despite the ability of left ventricular assist device as destination therapy (DT-LVAD) to prolong survival for many patients with advanced heart failure, little is known about the eventual end-of-life care that patients with DT-LVAD receive. METHODS AND RESULTS All patients undergoing DT-LVAD at the Mayo Clinic in Rochester, Minnesota, from January 1, 2007, to September 30, 2014, w...
متن کاملCost-effectiveness analysis of continuous-flow left ventricular assist devices as destination therapy.
BACKGROUND Continuous-flow left ventricular assist devices (LVADs) have become the dominant devices for mechanical circulatory support, but their cost-effectiveness is undetermined. This study assessed the cost-effectiveness of continuous-flow devices for destination therapy versus optimal medical management in advanced heart failure and compared the results with previous estimates for pulsatil...
متن کاملCost-Effectiveness Analysis of Continuous-Flow Left Ventricular Assist Devices as Destination Therapy
Mechanical circulatory support has become an accepted treatment for patients with advanced heart failure ineligible for transplantation. It is anticipated that the growing heart failure population coupled with the shortage of suitable donor organs will result in further increases in the use left ventricular assist devices (LVADs) as a means to enhance quality of life and survival. Critical eval...
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ژورنال
عنوان ژورنال: International Journal of Technology Assessment in Health Care
سال: 2007
ISSN: 0266-4623,1471-6348
DOI: 10.1017/s0266462307070365