Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery
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منابع مشابه
Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery
Despite the extensive media coverage associated with the diagnosis of chronic traumatic encephalopathy (CTE), our fundamental understanding of the disease pathophysiology remains in its infancy. Only recently have scientific laboratories and personnel begun to explore CTE pathophysiology through the use of preclinical models of neurotrauma. Some studies have shown the ability to recapitulate so...
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Progressive neurodegenerative diseases plague millions of individuals both in the United States and across the world. The current pathology of progressive neurodegenerative tauopathies, such as Alzheimer's disease (AD), Pick's disease, frontotemporal dementia (FTD), and progressive supranuclear palsy, primarily revolves around phosphorylation and hyperphosphorylation of the tau protein. However...
متن کاملChronic Traumatic Encephalopathy
42 The Hearing Journal May 2017 C oncussions are something of a clinical conundrum. There has been growing concern that one or more blows to the head can cause lasting brain damage, even after symptoms appear to have resolved. The diagnosis of concussions relies on the evaluation of multiple organ symptoms, but it is important to note that patient reports of their symptoms are inherently subjec...
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Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease that is a long-term consequence of single or repetitive closed head injuries for which there is no treatment and no definitive pre-mortem diagnosis. It has been closely tied to athletes who participate in contact sports like boxing, American football, soccer, professional wrestling and hockey. Risk factors include...
متن کاملChronic Traumatic Encephalopathy: The Impact on Athletes
Chronic traumatic encephalopathy (CTE) is a devastating neuropsychological condition afflicting a small percentage of athletes partaking in high-impact sports. The onset of symptoms lags years behind the inciting events. Repetitive minor head injuries are felt to be the main etiology behind CTE. Routine radiographic imaging generally is unremarkable in cases of CTE. Functional magnetic resonanc...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2015
ISSN: 1664-2295
DOI: 10.3389/fneur.2015.00223