Mode of action of thiocoraline, a natural marine compound with anti-tumour activity

Anti-MRSA activity of a bioactive compound produced by a marine Streptomyces and its optimization using statistical experimental design

Objective(s): To address the alarming problem of methicillin-resistant Staphylococcus aureus (MRSA), herein, a marine Streptomyces capable of producing an anti-MRSA compound has been studied.Materials and Methods: Strain MN41 was morphologically and physiologically characterized and then, molecularly identified using 16SrRNA analysis. To...

new applications of cuttlebone (cb) as a natural marine compound

detection of volatile compounds of medicinal plants with some nano-sorbents using modified or new methodologies and investigation of antioxidant activity of their methanolic extracts

in this work, a novel and fast method for direct analysis of volatile compounds (davc) of medicinal plants has been developed by holding a filament from different parts of a plant in the gc injection port. the extraction and analysis of volatile components of a small amount of plant were carried out in one-step without any sample preparation. after optimization of temperature, extraction time a...

Pyridalyl: A Novel Compound with Excellent Insecticidal Activity, High Selectivity, and Unique Mode of Action

Pyridalyl is a novel synthetic insecticide discovered by Sumitomo Chemical Co. Ltd. and has been developed globally as the trade names, Pleo, or Sumipleo. The compound is highly effective against various pests of Lepidoptera, Thysanoptera, Diptera and certain Acari, including resistant strains that are less susceptible or resistant to existing insecticides. The lepidopterous larvae treated with...

Anti-staphylococcal activity and mode of action of clofazimine.

OBJECTIVES Infections caused by Staphylococcus aureus might be treated with agents whose primary indications are for other infections. Clofazimine, an established anti-mycobacterial drug, could be such a candidate. However, the anti-staphylococcal properties of clofazimine have not been fully described and its mode of action, possibly involving inhibition of both RNA polymerase and a membrane-l...