Mixed connective tissue disease, undifferentiated connective tissue disease and overlap syndromes

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Mixed connective tissue disease, overlap syndromes, and eosinophilic fasciitis.

While the cause of connective tissue diseases (CTDs) remains unknown the classification of individual patients will continue to depend on identifying certain patterns of clinical and laboratory features. This is the basis of the various classification criteria for systemic sclerosis,'l systemic lupus erythematosus (SLE),2 and other connective tissue diseases. As many as 25% of patients with CTD...

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Overlap connective tissue syndromes.

Twenty six children with overlapping features of more than one connective tissue disorder are reported. The median age of onset was 9.5 years and median duration of follow up 7.5 years. Common presenting symptoms included arthritis, tenosynovitis. Raynaud's phenomenon, myositis, and rashes. At follow up 14 patients had developed sclerodermatous skin changes, but significant systemic involvement...

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[Mixed connective tissue disease].

Mixed connective tissue disease deserves to be a distinct disease entity due to the persistent citation of this disease in the literature since the original description by Sharp in 1972, in spite of the presence of several criticisms against the independency of this disease. The characteristic features of mixed connective tissue disease are: 1) the presence of anti-U1snRNP antibody with high ti...

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Mixed connective tissue disorder and Castleman's disease.

We present a 16-year-old girl who presented with polyarthritis in association with Raynaud's phenomenon, malar rash, oral ulcers, photosensitivity and alopecia of 6 months duration. On evaluation, it emerged that she had a mixed connective tissue disorder with a mesangio-proliferative glomerulonephritis. Her Chest radiograph revealed a well defined left mid and lower zone opacity with evidence ...

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Mixed connective tissue disease presenting myasthenia gravis.

We herein describe a 41-year-old female patient with an association of myasthenia gravis (MG) with anti-acetylcholine receptor (AcR) antibody, mixed connective tissue disease (MCTD) and Sjögren's syndrome (SjS). We reviewed the reported association of MG and MCTD, systemic lupus erythematosus, progressive systemic sclerosis, polymyositis and dermatomyositis, and SjS. Since we could find only tw...

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ژورنال

عنوان ژورنال: Almanac of Clinical Medicine

سال: 2019

ISSN: 2587-9294,2072-0505

DOI: 10.18786/2072-0505-2019-47-022