Mitochondrial uncoupler blocks metabolic disease
نویسندگان
چکیده
منابع مشابه
Metabolic testing in mitochondrial disease.
Mitochondrial oxidative phosphorylation (OXPHOS) disorders are a heterogeneous group of diseases with variable expression that often pose diagnostic dilemmas. Although definitive diagnosis of these disorders usually requires a muscle biopsy and mtDNA and enzymatic testing, standard metabolic studies including organic acid and amino acid analysis often provide useful findings that support an OXP...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2013
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd4212