Mitochondrial TCA cycle intermediates regulate body fluid and acid-base balance

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Mitochondrial TCA cycle intermediates regulate body fluid and acid-base balance.

Intrarenal control mechanisms play an important role in the maintenance of body fluid and electrolyte balance and pH homeostasis. Recent discoveries of new ion transport and regulatory pathways in the distal nephron and collecting duct system have helped to better our understanding of these critical kidney functions and identified new potential therapeutic targets and approaches. In this issue ...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2013

ISSN: 0021-9738

DOI: 10.1172/jci68095