Mitochondrial targeting of tBid/Bax: a role for the TOM complex?
نویسندگان
چکیده
منابع مشابه
The Translocase of the Outer Membrane of Mitochondria (TOM complex): Recognition of Mitochondrial Targeting Signals
CONTENTS 1. INTRODUCTION 1 1.1. Origin, structure and function of mitochondria 1 1.2. Preprotein import into mitochondria 2 1.3. Mitochondrial targeting signals 6 1.4. The TOM complex 7 1.5. BCS1 protein 10 1.6. Aims of the present study 12
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15 صفحه اولThe Tom Core Complex
Translocation of nuclear-encoded preproteins across the outer membrane of mitochondria is mediated by the multicomponent transmembrane TOM complex. We have isolated the TOM core complex of Neurospora crassa by removing the receptors Tom70 and Tom20 from the isolated TOM holo complex by treatment with the detergent dodecyl maltoside. It consists of Tom40, Tom22, and the small Tom components, Tom...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2009
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2009.61