منابع مشابه
Sending sisters their separate ways
S ister chromatids are often reluctant to separate during mitosis. Germann et al. show that a protein involved in DNA replication and repair helps eliminate lingering connections that can hold sister chromatids together (1). Sister chromatids tangle almost every time a cell enters mitosis. Unless the cell releases these links, the structures can break or fail to separate properly. Two kinds of ...
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In This Issue In This Issue Wnt separate ways, met later embers of the Wnt family of secreted signaling proteins control a wide range of developmental and pathological processes, with each Wnt protein signaling through either the " canonical " or " noncanonical " pathway. Two papers in this issue (and a Comment on page 753) now bring these two pathways together, showing that the noncanonical ca...
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from one Golgi complex to another under conditions that * Department of Molecular Cell Biology mirrored the conditions required for vesicle formation, Howard Hughes Medical Institute docking, and fusion. However, to many investigators University of California in the field, it remained uncertain whether the vesicles Berkeley, California 94720-3202 represented an obligatory intermediate in intra-...
متن کاملTime to Go Our Separate Ways: Opposite Effects of Study Duration on Priming and Recognition Reveal Distinct Neural Substrates
Amnesic patients have difficulties recognizing when stimuli are repeated, even though their responses to stimuli can change as a function of repetition in indirect tests of memory - a pattern known as priming without recognition. Likewise, experimental manipulations can impair recognition in healthy individuals while leaving priming relatively unaffected, and priming and recognition have been a...
متن کاملActivation of human platelets by misfolded proteins.
OBJECTIVE Protein misfolding diseases result from the deposition of insoluble protein aggregates that often contain fibrils called amyloid. Amyloids are found in Alzheimer disease, atherosclerosis, diabetes mellitus, and systemic amyloidosis, which are diseases where platelet activation might be implicated. METHODS AND RESULTS We induced amyloid properties in 6 unrelated proteins and found th...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2010
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1882iti2