miRs, miRs in the Wall, Who Is the Most Causative of Them All? ∗

The metaknowledge-based intelligent routing system (MIRS)

This paper addresses the issue of locating relevant information in a network of heterogeneous, unfederated information bases of various types, including structured databases, text, audio, picture and video ®les. The problem is to determine where the required information resides in a network, in locations unknown to the user. The objective is to construct a user-friendly, intelligent, search and...

MicroRNAs as Onco-miRs, drivers of cancer.

E vidence has been mounting for a decade that small regulatory RNAs called microRNAs (miRNAs) are linked to cancer formation and progression. But miRNAs ’ role as a driver of cancer has been less certain. Now animal studies are offering the fi rst tantalizing hints that some miRNAs, known as onco-miRs, can actually set tumor formation in motion and that restoring the function of tumor-suppressi...

Role of miRs in immune suppression

Tumors evade adaptive and/or innate immune response multiple mechanisms including loss and/or down-regulation of HLA class I antigens due to reduced or impaired expression of single or multiple components of the antigen processing machinery (APM), loss of costimulatory molecules, expression of co-inhibitory molecules including B7-H family members as well as of the non-classical HLA-G antigen. T...

Mirror, mirror on the wall, who is the fairest of them all?

romantic education:reading william wordsworths the prelude in the light of the history of ideas

عصر روشنگری زمان شکل گیری ایده های مدرن تربیتی- آموزشی بود اما تاکید بیش از اندازه ی دوشاخه مهم فلسفی زمان یعنی عقل گرایی و حس گرایی بر دقت و وضوح، انسان عصر روشنگری را نسبت به دیگر تواناییهایش نابینا کرده و موجب به وجود آمدن افرادی تک بعدی شد که افتخارعقلانیتشان، تاکید شان بر تجربه فردی، به مبارزه طلبیدن منطق نیاکانشان وافسون زدایی شان از دنیا وتمام آنچه با حواس پنجگانه قابل درک نبوده و یا در ...