MiR-signing gastrointestinal (con-)tract cancer

MiR-signing gastrointestinal (con-)tract cancer

MicroRNAs (miRs) are evolutionary conserved, small non-coding RNAs with a crucial role in regulating genes expression [1]. As they target simultaneously several genes, one miR can eventually control a variety of cellular functions. Therefore, aberrations in the expression of miRs have detrimental repercussions for disease development and progression, including cancer. In the current issue, the ...

Gastrointestinal Tract Cancer

Gastrointestinal Tract Cancer, edited by Martin Lipkin and Robert Good, is a valuable addition to the medical and surgical literature. Individual chapters are contributed by distinguished scientists and clinicians who, with the editors, are to be congratulated on the clarity of presentation and consistency of literary style of the volume as a whole. Figures, tables, and graphs are illustrative ...

Cancer of the upper gastrointestinal tract.

Gastrointestinal tract.

The developing gastrointestinal tract from conception to adolescence is in constant direct interaction with an increasingly complex environment. This sets up the potential for unrecognized acute as well as chronic disorders, some of which may be difficult to pinpoint in a developing infant and child, given the wide variations that exist. It is startling to note how early some environmental toxi...

miR-196, an Emerging Cancer Biomarker for Digestive Tract Cancers

Over the past decade, the emergence of microRNA (miRNA) research has firmly established this molecular family as a key component in cells. MiRNAs, which function as negative gene regulators, participate in multiple biological processes and maintain homeostasis in cells. The dysregulation of miRNA may contribute to numerous human disorders, including cancer. Recently, miR-196 was found to be abe...