منابع مشابه
miR-340 suppresses glioblastoma multiforme
Deregulation of microRNAs (miRs) contributes to tumorigenesis. Down-regulation of miR-340 is observed in multiple types of cancers. However, the biological function of miR-340 in glioblastoma multiforme (GBM) remains largely unknown. In the present study, we demonstrated that expression of miR-340 was downregulated in both glioma cell lines and tissues. Survival of GBM patients with high levels...
متن کاملTumor suppressive role of miR-194-5p in glioblastoma multiforme
Glioblastoma multiforme (GBM) is defined by the World Health Organization as the most aggressive form of grade IV glioma, characterized by unrestrained cellular proliferation. microRNAs (miRs) serve important roles in the pathogenesis of GBM. However, the function of miR‑194‑5p in GBM remains unknown. In the present study, the miR‑194‑5p levels in GBM tissues and cells were evaluated using the ...
متن کاملGlioblastoma Multiforme: A Single Hospital Experience
Background & Aim: Glioblastoma multiforme (GBM), the highest grade glioma (grade IV), is the most malignant form of astrocytoma in adults. This study aimed at evaluating the relationship between demographic, clinical and medical factors with GBM outcome. Methods & Materials/Patients: Through a cross-sectional design, 58 patients with newly diagnosed GBM were studied from 1999 to 2015 in Guil...
متن کاملRadiothermotherapy for glioblastoma multiforme: A preliminary study
Introduction: Glioblastoma multiforme (GBM) is a highly radioresistant cancer with low survival rate. Current therapy approaches have failed to treat GBM. The aim of this study was to assess how GBM tumors respond to combination of hyperthermia and radiotherapy. Materials and Methods: In this study, 38 GBM patients were included. 19 patients were treated ...
متن کاملGlioblastoma Multiforme
1 Penn State Institute of the Neurosciences and Penn State Cancer Institute, Hershey, PA 17033, USA 2The Ohio State University College of Medicine, Columbus, OH 43210, USA 3Departments of Health Evaluation Sciences and Neurosurgery, Penn State College of Medicine/Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA 4Radiation Oncology Brain Tumor Laboratory, University of Alabama...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2015
ISSN: 1949-2553
DOI: 10.18632/oncotarget.3288