miR-19a-3p Containing Exosomes Improve Cardiac Function in Ischemic Myocardium
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چکیده
منابع مشابه
5-lipoxygenase is a direct target of miR-19a-3p and miR-125b-5p.
5-Lipoxygenase (5-LO) is the key enzyme in leukotriene biosynthesis. Leukotrienes are mediators of the innate immune system and inflammatory processes, and they might also be involved in cancer development. MicroRNAs (miRNAs) are important translational regulators and have been shown to be involved in development, differentiation, and cancer. Unraveling the miRNA network is important for unders...
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Transforming growth factor-β1 (TGF-β1) plays an important role on fibrogenesis in heart disease. MicroRNAs have exhibited as crucial regulators of cardiac homeostasis and remodeling in various heart diseases. MiR-19a-3p/19b-3p expresses with low levels in the plasma of heart failure patients. The purpose of our study is to determine the role of MiR-19a-3p/19b-3p in regulating autophagy-mediated...
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ژورنال
عنوان ژورنال: The Thoracic and Cardiovascular Surgeon
سال: 2018
ISSN: 0171-6425,1439-1902
DOI: 10.1055/s-0038-1627831