MiR-146a rs2910164 G/C polymorphism and gastric cancer susceptibility: a meta-analysis
نویسندگان
چکیده
منابع مشابه
Association of miR-146a rs2910164 and miR-27a rs895819 polymorphisms with type 2 diabetes susceptibility: A Meta-Analysis
Background and Aim: Several investigations have evaluated the association of miR-146a rs2910164 and miR-27a rs895819 single-nucleotide polymorphisms with susceptibility to type 2 diabetes (T2D). However, the findings are conflicting and inconclusive. Therefore, this meta-analysis performed to investigate the association between these polymorphisms and T2D risk. Methods: Studies were identifie...
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BACKGROUND MicroRNAs regulate gene expression at the post-transcriptional level and involved in diverse biological and pathological processes, including tumorigenesis. Rs11614913 in miR-196a2 and rs2910164 in miR-146a are shown to associate with increased/decreased cancer risk. We performed a meta-analysis to systematically summarize the possible association. METHODOLOGY/PRINCIPAL FINDINGS We...
متن کاملThe miR-146a rs2910164 G > C polymorphism and susceptibility to digestive cancer in Chinese.
BACKGROUND Several studies have reported the role of the miR-146a rs2910164 G > C polymorphism as a susceptibility factor for several digestive cancers. However, the results have been controversial. Therefore, we conducted the present meta-analysis to obtain the most reliable estimate of the association. METHODS PubMed, Embase and Web of Science databases were searched. Crude odds ratios (ORs...
متن کاملGenetic variant of miR-146a rs2910164 C>G and gastric cancer susceptibility
The single nucleotide polymorphism (SNP) rs2910164 G>C within miR-146a has been reported that is associated with the increased risk of gastric cancer (GCa). However, the results are inconclusive, espicially among Asian populations, which probably due to small sample size in each single study. To validate this association and get a more precise estimation, we conducted a large GCa study includin...
متن کاملMiR-146a rs2910164 polymorphism is associated with hepatocellular carcinoma: a meta-analysis.
Results of published studies on the association between the miR-146a rs2910164 polymorphism and the risk of hepatocellular carcinoma (HCC) were inclusive. We performed a meta-analysis. A literature research was conducted using PubMed, Cochrane Library, Ovid, Embase, Wanfang and China National Knowledge Infrastructure (CNKI) databases, to identify studies. Statistical analyses were conducted in ...
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ژورنال
عنوان ژورنال: BMC Medical Genetics
سال: 2014
ISSN: 1471-2350
DOI: 10.1186/s12881-014-0117-2