Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting
نویسندگان
چکیده
منابع مشابه
Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting
In this work, we examined enhanced skin delivery of minoxidil applied in nanoemulsions incorporating skin penetration enhancers. Aliquots of fully characterized oil-in-water nanoemulsions (1 mL), containing minoxidil (2%) and the skin penetration enhancer oleic acid or eucalyptol as oil phases, were applied to full-thickness excised human skin in Franz diffusion cells, while aqueous solutions (...
متن کاملOptimization of Ibuprofen Delivery through Rat Skin from Traditional and Novel Nanoemulsion Formulations
The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it i...
متن کاملOptimization of Ibuprofen Delivery through Rat Skin from Traditional and Novel Nanoemulsion Formulations
The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it i...
متن کاملoptimization of ibuprofen delivery through rat skin from traditional and novel nanoemulsion formulations
the topical delivery of non-steroidal anti-inflammatory drugs (nsaids) such as ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. however, it is dif...
متن کاملOptimization of Ibuprofen Delivery through Rat Skin from Traditional and Novel Nanoemulsion Formulations
The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it is dif...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2018
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics10010019