منابع مشابه
Ramy H . Bishay The ‘ Mighty Mouse
Tissue rejection remains a major problem in organ transplantation. The use of experimental animal models continues to enhance our understanding of the rejection process and offers strategies for its prevention. The popular mouse model of heterotopic cardiac transplantation has been used for over three decades to help investigators understand the pathogenesis of graft rejection and in turn, how ...
متن کاملA mighty mouse: building a better model of multiple sclerosis.
The 2 cardinal cell populations mediating adaptive immunity are T and B lymphocytes. These cells play important but poorly understood roles in the immunopathological demyelinating disease multiple sclerosis (MS) and in a widely used animal model of human MS known as EAE. In the current issue of the JCI, 2 research teams report their parallel studies of double-transgenic mice expressing T and B ...
متن کاملThe mighty mite
storehouses of terrestrial biodiversity, but many of the more astounding species are apparent only after the closest scrutiny. Here are a few of the roughly 2000 species of mite (Arachnida: Acari) that can be found in the subtropical rainforests of Lamington National Park in southeast Queensland, Australia. The mites there range in size from 0.182 millimetres to 7 millimetres, with the minute b...
متن کاملMicroexons--tiny but mighty.
The landscape of alternative splicing is only beginning to unravel, and the functional consequences are often unclear. Two articles in Cell and Genome Research focus on a set of largely ignored yet highly conserved exons, microexons. These appear strongly regulated by RNA-binding proteins (RBPs) and functionally modulate protein–protein interactions with strong evidence for deregulation in auti...
متن کاملCod all mighty
The importance of fish in the history of Europe, particularly in Catholic countries, and the European colonisation of North America, have been underplayed, according to a new book by University of California anthropologist, Brian Fagan. Most Americans have been traditionally schooled to believe that the European discovery and settlement of the New World arose from two events: the first voyage o...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2002
ISSN: 0009-7330,1524-4571
DOI: 10.1161/res.90.3.244