Microtubules: A dynamic target in cancer therapy
نویسندگان
چکیده
منابع مشابه
Dynamic Simulation and Mechanical Properties of Microtubules
This work is conducted to obtain mechanical properties of microtubule. For this aim, interaction energy in alpha-beta, beta-alpha, alpha-alpha, and beta-beta dimers was calculated using the molecular dynamic simulation. Force-distance diagrams for these dimers were obtained using the relation between potential energy and force. Afterwards, instead of each tubulin, one sphere with 55 KDa weight ...
متن کاملThe Canonical Wnt Signaling (Wnt/β-Catenin Pathway): A Potential Target for Cancer Prevention and Therapy
Precise regulation of signal transduction pathways is crucial for normal animal development and for maintaining cellular and tissue homeostasis in adults. The Wnt/Frizzled-mediated signaling includes canonical and non-canonical signal transduction pathways. Upregulation or downregulation of the canonical Wnt-signaling (or the Wnt/β-Catenin signal transduction) leads to a variety of human diseas...
متن کاملP14: Mitochondria as a Target for Drug Therapy in Epilepsy
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملTarget Therapy in Gastric Cancer
Gastric cancer is the fifth most frequently diagnosed cancer and the third leading cause of cancer mortality. In advanced gastric cancer patients, the treatment outcomes are dismal. With the development of the molecular targeted therapy, the prognosis in patients with advanced and unresectable gastric cancer are improved. This article reviewed the molecular targeted agents in clinical use, thei...
متن کاملThe Role of MRSI in Target Volume Definition for Radiation Therapy of Prostate Cancer
Introduction: Recently, magnetic resonance spectroscopic imaging (MRSI), as a functional imaging method, has been used for clinical target volume definition. In this study, we used this method to define the target volume in prostate radiotherapy. Material and Method: In this study, we used images of 20 prostate cancer cases. MRSI and MRI images were fused with CT images. Then, treatment plannin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IUBMB Life
سال: 2008
ISSN: 1521-6543,1521-6551
DOI: 10.1002/iub.25