Microscopic-Observation Drug-Susceptibility Assay for the Diagnosis of TB
نویسندگان
چکیده
منابع مشابه
Microscopic-observation drug-susceptibility assay for the diagnosis of TB.
BACKGROUND New diagnostic tools are urgently needed to interrupt the transmission of tuberculosis and multidrug-resistant tuberculosis. Rapid, sensitive detection of tuberculosis and multidrug-resistant tuberculosis in sputum has been demonstrated in proof-of-principle studies of the microscopic-observation drug-susceptibility (MODS) assay, in which broth cultures are examined microscopically t...
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INTRODUCTION Limited data exist on use of the microscopic-observation drug-susceptibility (MODS) assay among persons suspected of MDR-TB living in high HIV-prevalence settings. METHODS We retrospectively reviewed available clinical and drug susceptibility data for drug-resistant TB suspects referred for culture and drug-susceptibility testing between April 1, 2011 and March 1, 2012. The diagn...
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BACKGROUND Liquid culture systems are more rapid and sensitive for both the detection and drug susceptibility testing (DST) of Mycobacterium tuberculosis. SETTING St Peter's TB Specialised Hospital and public health laboratory, Addis Ababa. OBJECTIVE To compare the microscopic-observation drug susceptibility (MODS) assay with the BACTEC-MGIT 960 system for isoniazid and rifampicin DST (i.e....
متن کاملPerformance of the microscopic observation drug susceptibility assay in drug susceptibility testing for Mycobacterium tuberculosis.
The drug susceptibility testing performance of a broth-based method with microscopic reading of bacillary growth, the microscopic observation drug susceptibility (MODS) assay, was compared to that of the reference 7H10 agar method of proportion by using 53 isolates of Mycobacterium tuberculosis from persons at risk for multidrug-resistant TB. For isoniazid (0.1 micro g/ml) and rifampin (2.0 mic...
متن کاملEvaluation of microscopic observation drug susceptibility assay for diagnosis of multidrug-resistant Tuberculosis in Viet Nam
BACKGROUND Early diagnosis of tuberculosis (TB) and multidrug resistant tuberculosis (MDR TB) is important for the elimination of TB. We evaluated the microscopic observation drug susceptibility (MODS) assay as a direct rapid drug susceptibility testing (DST) method for MDR-TB screening in sputum samples METHODS All adult TB suspects, who were newly presenting to Pham Ngoc Thach Hospital from...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2006
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa055524