microRNAs suppress cellular phenotypic heterogeneity

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microRNAs suppress cellular phenotypic heterogeneity

microRNAs are small noncoding RNAs that reduce protein output from complementary target mRNA transcripts. They are a conserved family of gene regulators in multicellular organisms, targeting much of the transcriptome. This pervasiveness is at odds with their generally modest repressive capacity, and suggests that microRNAs might not be cellular decision makers; rather they might ensure the stab...

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ژورنال

عنوان ژورنال: Cell Cycle

سال: 2014

ISSN: 1538-4101,1551-4005

DOI: 10.4161/cc.29013