MicroRNAs Contribute to Breast Cancer Invasiveness

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

MicroRNAs and Breast Cancer

MicroRNAs are a class of small non-coding RNAs that are involved in the negative regulation of gene expression primarily through binding to the 3’untranslated region of their target mRNA. MicroRNAs have multiple mRNA targets, each of which can be regulated by multiple microRNAs making this a complex regulatory network. The identification of their importance in different types of cancer and vali...

متن کامل

Exosome-derived microRNAs contribute to prostate cancer chemoresistance.

Certain microRNAs (miRNAs) play a key role in cancer cell chemoresistance. However, the pleiotropic functions of exosome-derived miRNAs on developing chemoresistance remain unknown. In the present study, we aimed to construct potential networks of miRNAs, which derived from the exosome of chemoresistant prostate cancer (PCa) cells, with their known target genes using miRNA expression profiling ...

متن کامل

Does architectural lighting contribute to breast cancer?

OBJECTIVES There is a growing interest in the role that light plays on nocturnal melatonin production and, perhaps thereby, the incidence of breast cancer in modern societies. The direct causal relationships in this logical chain have not, however, been fully established and the weakest link is an inability to quantitatively specify architectural lighting as a stimulus for the circadian system....

متن کامل

GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness

Kisspeptins (Kp), peptide products of the Kisspeptin-1 (KISS1) gene are endogenous ligands for a G protein-coupled receptor 54 (GPR54). Previous findings have shown that KISS1 acts as a metastasis suppressor in numerous cancers in humans. However, recent studies have demonstrated that an increase in KISS1 and GPR54 expression in human breast tumors correlates with higher tumor grade and metasta...

متن کامل

Heregulin and Agonistic Anti p185 B2 Antibodies Inhibit Proliferation But Increase Invasiveness of Breast Cancer Cells That Overexpress pl8scerbB2: Increased Invasiveness May Contribute to Poor Prognosis1

Overexpression of p185c rbB2 (p185/ EU/}fE ) by tumor cells is associated with a poor prognosis in many but not all studies of breast and ovarian cancer. The poor prognosis associated with overexpression of p185cerbB2 could result from an increased growth rate or increased invasive potential. The p185cerbB2 tyrosine kinase receptor can be activated with agonistic antibodies directed against p18...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Cells

سال: 2019

ISSN: 2073-4409

DOI: 10.3390/cells8111361