Microglia and neurogenesis in the epileptic dentate gyrus
نویسندگان
چکیده
منابع مشابه
Microglia and neurogenesis in the epileptic dentate gyrus.
Microglia are recognized as major immune cells in the brain. They have been traditionally studied in various contexts of disease, where their activation has been assumed to induce mostly detrimental effects. Recent studies, however, have challenged the current view of microglia, clarifying their essential contribution to the development of neural circuits and brain function. In this review, we ...
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Neuropeptide Y (NPY) has been shown to depress hyperexcitable activity that has been acutely induced in the normal rat brain. To test the hypothesis that NPY can also reduce excitability in the chronically epileptic human brain, we recorded intracellularly from dentate granule cells in hippocampal slices from patients with hippocampal seizure onset. NPY had a potent and long-lasting inhibitory ...
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ژورنال
عنوان ژورنال: Neurogenesis
سال: 2016
ISSN: 2326-2133
DOI: 10.1080/23262133.2016.1235525