Microfluidic effects of transporting signaling components in cell coculture chips
نویسندگان
چکیده
منابع مشابه
Liver-kidney Microfluidic Bioreactor for Cell Coculture in Drug Studies
A microfluidic bioreactor for cell co-culture has been developed to study the cytotoxicity of xenobiotics in multiorgan interaction models. In this paper, we investigate the drug metabolism of ifosfamide, an anticancer drug, in liver and its impact on kidney. HepG2/C3A (liver) and MDCK (kidney) cells are cultured in two separate PDMS chambers connected by a perfusion loop mimicking blood flow. ...
متن کاملWhole-Teflon microfluidic chips.
Although microfluidics has shown exciting potential, its broad applications are significantly limited by drawbacks of the materials used to make them. In this work, we present a convenient strategy for fabricating whole-Teflon microfluidic chips with integrated valves that show outstanding inertness to various chemicals and extreme resistance against all solvents. Compared with other microfluid...
متن کاملIntegration of Silica Aerogels in Microfluidic Chips
This paper reports a method to integrate silica aerogels monolithically in microfluidic chips. Silica Aerogel is a highly porous bulk material. The gel was synthesized from tetraethyl orthosilicate by a sol-gel process. Polyethylene glycol and an extended aging period were used to strengthen the matrix minimizing gel shrinkage. This technique allows alcogel structures with high strength and sti...
متن کاملMicrofluidic Chips for Liposome Production
In recent years, the development of nanoand micro-particles has attracted considerable 11 interest from researchers and enterprises, because of the potential utility of such particles as drug 12 delivery vehicles. Amongst the different techniques employed for the production of nanoparticles, 13 microfluidic-based methods have proven to be the most effective for controlling particle size and 14 ...
متن کاملMicrofluidic Chips for Semen Analysis
The gold standard of semen analysis is still an manual method, which is time-consuming, labour intensive and needs thorough quality control. Microfluidics can also offer advantages for this application. Therefore a first step in the development of a microfluidic chip has been made, which enables the man the semen analysis at home. In this article recent efforts to determine the concentration an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Microfluidics and Nanofluidics
سال: 2008
ISSN: 1613-4982,1613-4990
DOI: 10.1007/s10404-008-0304-6