MicroED: tiny crystals, big opportunities

Tiny Medicine, Big World

Phasing tiny crystals

For tiny crystals, their diffraction intensities at and between the Bragg peaks become measurable due to the limited number of the unit cells, which can in principle be used to directly phase the crystal structures.

Thinking Big About Tiny Databases

Work on early tiny database systems, like TinyDB [17] and Cougar [23] has shown that a declarative approach can provide a powerful and easy to use interface for collecting data from static sensor networks. These early systems, however, have significant limitations; in particular, they are useful only for low-rate data collection applications on static sensor networks and they don’t integrate we...

Big Projects Targeting Tiny Pathogens

Big lab on a tiny chip.

■ Ultimately, consumers could have labs-on-chips in their home for fast diagnosis of common illnesses. —The Editors Imagine shrinking the beakers, eyedroppers, chemicals and heaters of a chemistry lab onto a little microchip that could dangle from a key chain. A growing number of companies and universities are claiming to have devised such marvels, ready to perform vital analyses from detecting...