منابع مشابه
Gut Microbiota Elicits a Protective Immune Response against Malaria Transmission
Glycosylation processes are under high natural selection pressure, presumably because these can modulate resistance to infection. Here, we asked whether inactivation of the UDP-galactose:β-galactoside-α1-3-galactosyltransferase (α1,3GT) gene, which ablated the expression of the Galα1-3Galβ1-4GlcNAc-R (α-gal) glycan and allowed for the production of anti-α-gal antibodies (Abs) in humans, confers...
متن کاملDeveloping transmission-blocking strategies for malaria control
Analysis of the varied developmental pathways exploited by malarial parasites as they pass through their differing life stages can be challenging [1–3], the parasites often adopting mechanisms that differ from the conventional norms of their eukaryotic hosts. It is, however, these unexpected differences that provide fascination and drive to the basic research scientist and simultaneously expose...
متن کاملOptimal Control of Malaria Transmission: Analysis of Mosquito’s Bias
It is well-known that mosquitoes like specific smell or odor from the human so that some people is likely to be bitten more than other people. In recent years, it was investigated that mosquitoes like people more who has malaria parasite, especially gametocyte. This effect is called a mosquito-bias effect. As the dynamics of vector-borne disease is highly related to vector’s behavior, it is wor...
متن کاملOptimal Control Strategy of Plasmodium vivax Malaria Transmission in Korea
OBJECTIVE To investigate the optimal control strategy for Plasmodium vivax malaria transmission in Korea. METHODS A Plasmodium vivax malaria transmission model with optimal control terms using a deterministic system of differential equations is presented, and analyzed mathematically and numerically. RESULTS If the cost of reducing the reproduction rate of the mosquito population is more tha...
متن کاملIdentification of hot spots of malaria transmission for targeted malaria control.
BACKGROUND Variation in the risk of malaria within populations is a frequently described but poorly understood phenomenon. This heterogeneity creates opportunities for targeted interventions but only if hot spots of malaria transmission can be easily identified. METHODS We determined spatial patterns in malaria transmission in a district in northeastern Tanzania, using malaria incidence data ...
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ژورنال
عنوان ژورنال: Trends in Parasitology
سال: 2016
ISSN: 1471-4922
DOI: 10.1016/j.pt.2015.11.004