MICROBIAL PRODUCTION OF L-LYSINE

Microbial Production of L-lysine I. Production by Auxotropiis of Brevibacterium Elavum

Seven homoserine, 42 methionine, 42 threonine, and 15 isoleucine auxotrophs were obtained from Brevibacterium flavum No. 2247 (ATCC No. 14067) by X-ray irradiation and N-methyl-N'-nitro-N-nitrosoguanidine treatment. Concerning the L-lysine-producing ability, the homoserine auxotrophs were the best and about one-half of the threonine auxotrophs ranked next. The rest of threonine auxotrophs and a...

microbial production of lysine using whey permeate and molasses

lysine is nutritionally essential for humans and animals. it cannot be synthesized biologically in body. children and growing animals have a high requirement of lysine, since it is needed for bone formation. therefore, it must be added to food and feed supplement to improve the protein quality. in addition, lysine has some pharmaceutical applications in the formulation of diets with balanced am...

Enzymatic production of 5-aminovalerate from l-lysine using l-lysine monooxygenase and 5-aminovaleramide amidohydrolase

5-Aminovalerate is a potential C5 platform chemical for synthesis of valerolactam, 5-hydroxyvalerate, glutarate, and 1,5-pentanediol. It is a metabolite of l-lysine catabolism through the aminovalerate pathway in Pseudomonas putida. L-Lysine monooxygenase (DavB) and 5-aminovaleramide amidohydrolase (DavA) play key roles in the biotransformation of L-lysine into 5-aminovalerate. Here, DavB and D...

Microbial production of xylitol, L-xylulose and L-xylose

Aalto University, P.O. Box 11000, FI-00076 Aalto www.aalto.fi Author Anne Usvalampi Name of the doctoral dissertation Publisher School of Chemical Technology Unit Department of Biotechnology and Chemical Technology Series Aalto University publication series DOCTORAL DISSERTATIONS 137/2013 Field of research Bioprocess Engineering Manuscript submitted 4 June 2013 Date of the defence 25 October 20...

Enhanced production of L-lysine from Corynebacterium glutamicum by mutagenesis