Microbial keratitis and the selection of topical antimicrobials

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Microbial keratitis and the selection of topical antimicrobials

Microbial keratitis is a major cause of corneal opacity and loss of vision worldwide, and topical antimicrobial therapy is a critical component in its management. The study by Austin et al found that there are regional variations in practice patterns influenced by concern over availability and toxicity versus broad-spectrum coverage and resistance. Respondents in the USA were more likely to tre...

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Bacterial susceptibility to topical antimicrobials and clinical outcome in bacterial keratitis.

PURPOSE To investigate the relationship between the susceptibility of bacteria to topical antimicrobials and clinical outcome in microbial keratitis. METHODS Clinical outcome data were collected from patients with microbial keratitis from whom a bacterium had been isolated during the period 2003 to 2006. The minimum inhibitory concentration (MIC) was determined for the isolates against 10 ant...

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Topical Antimicrobials in Wounds

Wounds are a major cause of morbidity especially diabetic foot wounds. Topical antimicrobials are frequently used in day to day practice mainly in management of wounds by various healthcare professionals ranging from general practitioner to specialist surgeons. However lot of controversies exists regarding the usage of antimicrobials. This article provides an insight on the usage of various com...

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Topical Antimicrobials and the Open Surgical Wound.

BACKGROUND Topical antiseptic and antibiotic agents have been used for the prevention of surgical site infections since Joseph Lister's original research on this subject. Although these agents are used extensively in clinical practice, evidence to support the use of topical antimicrobial agents remains limited. PATIENTS AND METHODS The world literature on the use of antiseptic and antibiotic ...

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Topical corticosteroids and fungal keratitis.

The incidence of experimentally produced keratitis with Candida albicans was studied in traumatized rabbit eyes; these eyes, 23 out of 30 treated with 1 per cent hydrocortisone drops, 16 out of 30 treated with 1 per cent medrysone drops, and 12 out of 30 treated with control drops without corticosteroid, developed infection as demonstrated by culture of corneal tissue. The increased number of i...

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ژورنال

عنوان ژورنال: BMJ Open Ophthalmology

سال: 2017

ISSN: 2397-3269

DOI: 10.1136/bmjophth-2017-000086