MGMT and MSH6 immunoexpression for functioning pituitary macroadenomas
نویسندگان
چکیده
منابع مشابه
Fsrt for Pituitary Macroadenomas
The use of fractionated stereotactic radiotherapy (FSRT) has evolved with technical advances in noninvasive immobilization, radiation delivery, and image guidance. The application of FSRT to pituitary tumours is aimed at reducing toxicity through improved dose conformality and reduced treatment margins. The aim of the present paper is to report our own experience and to review the published dat...
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OBJECTIVE The prevalence of hyperprolactinemia in non-functioning pituitary macroadenomas (NFPMAs) is not well known, and hyperprolactinemia caused by a NFPMA is currently associated with diagnostic uncertainty. Thus, the aim of this study was to evaluate the prevalence of hyperprolactinemia in NFPMAs. METHODS A meta-analysis of all existing articles in PubMed was conducted. The search string...
متن کاملCushing's disease: a comparison of pituitary corticotroph microadenomas and macroadenomas.
Cushing's disease appears as a functionally heterogeneous disease, but criteria that are able to distinguish between different clinical forms remain elusive. We compared two subgroups of patients with proven Cushing's disease according to the size of the pituitary adenoma, evaluated by computed tomography or magnetic resonance imaging. Our series comprised 11 patients with a microadenoma and 10...
متن کاملThree-dimensional reconstruction and morphological characterization of pituitary macroadenomas
INTRODUCTION The aim was to investigate the relationship between the tumor (clinicopathologic and radiological) characteristics and the morphological parameters of pituitary macroadenoma or giant adenoma patients using a three-dimensional (3D) reconstructed model. MATERIAL AND METHODS Magnetic resoanance imaging (MRI) was performed preoperatively; tumor grade was determined by the Knosp-Stein...
متن کاملClinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas.
OBJECTIVE It was to assess the main characteristics of patients undergoing pituitary tumor surgery. METHOD Eighty-seven patients (44 men; 44.8±13 years old) were included. RESULTS The main symptoms were visual alterations (87.3%), headache (70.1%), diminished libido (34.4%), galactorrhea (22.9%) and hair loss (19.5%). The axes affected were gonadotropic (72.6%), thyrotropic (48.4%) and cort...
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ژورنال
عنوان ژورنال: Pituitary
سال: 2017
ISSN: 1386-341X,1573-7403
DOI: 10.1007/s11102-017-0829-3