Methylprednisolone pulse therapy for severe immune thrombocytopenia associated with infectious mononucleosis

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Natural history of severe thrombocytopenia in infectious mononucleosis.

The natural history of severe thrombocytopenia in two patients with infectious mononucleosis (minimum platelet counts under 10 x 109 and 17 x 109/1 respectively) is described. In both, the platelet count rose rapidly and spontaneously, reaching approximately 100 x 109l/l on the seventh day. Bleeding symptoms were also transient and never life-threatening. The possibility of very rapid spontaneo...

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Intravenous pulse methylprednisolone in chronic idiopathic thrombocytopenia.

Two children with chronic idiopathic thrombocytopenic purpura unresponsive to either standard corticosteroid treatment or high dose intravenous gammaglobulin, or both, were treated with intravenous methylprednisolone (15 mg/kg/day) given in pulses over three consecutive days. Both children showed a positive response and are still in remission after three months.

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Immune Thrombocytopenia Associated with Hepatitis A Infection in Children

Hepatitis A infection is usually a self–limited disease during childhood. Autoimmune manifestations are rarely reported among patients with HA infection. We describe a previously healthy 6-yr-old male with acute hepatitis A who developed immune thrombocytopenia.

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severe active ulcerative colitis and resistance to intravenous hydrocortisone therapy: successful treatment with methylprednisolone pulse therapy

ulcerative colitis is a mucosal-inflammatory disease that usually involves the rectum and extends proximally to involve all or part of the colon. medications for treatment include anti-inflammatory agents such as 5-asa compounds, systemic and topical corticosteroids and immunomodulators. a 33 year-old female and 52 year-old male both diagnosed with severe active ulcerative colitis who were resi...

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 2007

ISSN: 0361-8609,1096-8652

DOI: 10.1002/ajh.20825