Methylome Analysis and Epigenetic Changes Associated with Menarcheal Age

نویسندگان
چکیده

منابع مشابه

Methylome Analysis and Epigenetic Changes Associated with Menarcheal Age

Reproductive factors have been linked to both breast cancer and DNA methylation, suggesting methylation as an important mechanism by which reproductive factors impact on disease risk. However, few studies have investigated the link between reproductive factors and DNA methylation in humans. Genome-wide methylation in peripheral blood lymphocytes of 376 healthy women from the prospective EPIC st...

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High-resolution analysis of epigenetic changes associated with X inactivation.

Differentiation of female murine ES cells triggers silencing of one X chromosome through X-chromosome inactivation (XCI). Immunofluorescence studies showed that soon after Xist RNA coating the inactive X (Xi) undergoes many heterochromatic changes, including the acquisition of H3K27me3. However, the mechanisms that lead to the establishment of heterochromatin remain unclear. We first analyze ch...

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Menarcheal age among Indian sportswomen.

The subjects of the study were 85 Indian sportswomen from Delhi and the states of Uttar Pradesh, Punjab and Gujarat, and included outstanding players of cricket, hockey, kho-kho and table-tennis, who were winners of university, state or national championships. A sample of 77 subjects selected at random was used as the control. The recall procedures suggested by Damon and Bajema (1974) were used...

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Accessing epigenetic variation in the plant methylome.

Cytosine DNA methylation is the addition of a methyl group to the 5' position of a cytosine, which plays a crucial role in plant development and gene silencing. Genome-wide profiling of DNA methylation is now possible using various techniques and strategies. Using these technologies, we are beginning to elucidate the extent and impact of variation in DNA methylation between individuals and/or t...

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Menarcheal age in Ghanaian school girls.

In a cross-sectional retrospective study of 2087 Ghanaian school girls in various educational institutions in the Kumasi district, Ashanti region, Ghana, the mean menarcheal age was found to be 13.98 +/- 1.42 years. Differences in the menarcheal age of the girls was found to be significantly correlated to social class, parents ethnic origin, educational institution and home living area (P = 0.0...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0079391