Methacholine responsiveness in infants assessed with low frequency forced oscillation and forced expiration techniques

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Methacholine responsiveness in infants assessed with low frequency forced oscillation and forced expiration techniques.

BACKGROUND The contribution of the pulmonary tissues to the mechanical behaviour of the respiratory system is well recognised. This study was undertaken to detect airway and lung tissue responses to inhaled methacholine (Mch) using the low frequency forced oscillation technique (LFOT). METHODS The respiratory system impedance (Zrs, 0.5-20 Hz) was determined in 17 asymptomatic infants. A model...

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Bronchial responsiveness to histamine and methacholine measured with forced expirations and with the forced oscillation technique.

The objective of this study was to compare bronchial challenge tests with two substances [histamine (H) and methacholine (M)] and two methods of measuring the effect parameter FEV1 and pulmonary impedance [with the forced oscillation technique (FOT)] in order to determine which test is the shortest, and gives the least (drug) load to the patient. Furthermore, it was considered whether the resul...

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The diagnostic capacity of forced oscillation and forced expiration techniques in identifying asthma by isocapnic hyperpnoea of cold air.

The measurement of forced expiratory volume in one second (FEV1) is often used to assess the effect of bronchial provocations, and deep inspiration is required beforehand. This may briefly alter the bronchial tone in a variable way in some subjects. The forced oscillation technique (FOT) is a test used to characterize the mechanical impedance of the respiratory system, and prior deep inspiratio...

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Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness

BACKGROUND Pulmonary function has been reported in mice using negative pressure-driven forced expiratory manoeuvres (NPFE) and the forced oscillation technique (FOT). However, both techniques have always been studied using separate cohorts of animals or systems. The objective of this study was to obtain NPFE and FOT measurements at baseline and following bronchoconstriction from a single cohort...

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No effect of oral high frequency oscillation combined with forced expiration manoeuvres on tracheobronchial clearance in chronic bronchitis.

This study compared the effect of oral high frequency oscillation (OHFO) with the effect of the forced expiration technique (FET) on tracheobronchial clearance. Eight patients with chronic bronchitis were investigated (mean age 60 +/- 10 yrs, mean forced expiratory volume in one second (FEV1) 68 +/- 27% predicted, mean sputum production 33 +/- 9 g.day-1). OHFO was applied at the respiratory sys...

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ژورنال

عنوان ژورنال: Thorax

سال: 2001

ISSN: 0040-6376

DOI: 10.1136/thorax.56.1.42