Metal ion chelation and anti-glycation properties of polysaccharides of Phyllanthus amarus plant

نویسندگان

چکیده

The study was conducted to investigate the in vitro anti-glycation activity of Phyllanthus amarus plant extract. above has been used for centuries its useful health benefits variety inflammatory diseases. In current study, antioxidant, metal chelating and ferric ion reducing antiglycation property studied polysaccharides isolated from At 25 μg/mL sugar concentration Vitamin C, gave 57 % 65 inhibition hydroxyl radical scavenging assay Antiglycation extract vitamin C showed 65% 87% respectively. It also had (PAPE 74%, Ascorbic acid 88%) by PAPE IS about 68% when compared standard chelator EDTA 90%. inhibited fructosamine formation 52% after 3 days incubation. studies an opinion that glycation exhibited due free but modification amino or carbonyl groups resulted formation. may be donating hydrogen atom radical, exhibiting antioxidant activity. So polysaccharide use preventing many radicals induced diseases delaying complications diabetes.

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ژورنال

عنوان ژورنال: GSC biological and pharmaceutical sciences

سال: 2021

ISSN: ['2581-3250']

DOI: https://doi.org/10.30574/gscbps.2021.15.03.0190