منابع مشابه
Metabolites of piperidine in rat urine.
Piperidine is one of pharmacologically active biogenic amines. While two pathways for piperidine production have been reported, little is known about metabolism of the compound. In the present study, piperidine and its hydroxylated, conjugated and unknown metabolites were detected in rat urine by radiochromatographic analysis. Using GC-MS technique, it was confirmed that 3-hydroxypiperidine and...
متن کاملIdentification of metabolites of octamethylcyclotetrasiloxane (D(4)) in rat urine.
Octamethylcyclotetrasiloxane (D(4)) is an industrial chemical of significant commercial importance. In this study, its major urinary metabolites were identified. The urine samples described here were collected from male and female Fischer rats (F-344) administered [(14)C]D(4) i.v. The metabolite profile was obtained using an HPLC system equipped with a radioisotope detector. HPLC analysis was p...
متن کاملHormone Metabolites in Dried Urine
Steroid hormones are low molecular weight, lipid-like molecules that are synthesized from cholesterol mostly in specialized glands such as the adrenals, ovaries, and testes. Once synthesized, these steroids are released into the bloodstream where they enter target tissues/cells and bind to specific hormone receptors. There, the hormone-receptor complex activates specific gene sites and stimulat...
متن کاملProfile of volatile metabolites in human urine.
Volatile constituents of 30 urines from 10 adults have been studied by gas chromatography, and two also by mass spectrometry. The sample was prepared by extracting urine with ethyl ether, distilling the extract at low temperature under reduced pressure, and concentrating the distillate to a few microliters. High-efficiency capillary columns, 150 m X 0.5 mm i.d., provide the resolution necessary...
متن کاملPharmacokinetics of alkylresorcinol metabolites in human urine.
Wholegrain cereals are reported to promote beneficial health effects. Wholegrain wheat and rye are almost exclusive sources of alkylresorcinols, and intact alkylresorcinols together with their plasma and urinary metabolites, 3-(3,5-dihydroxyphenyl)-1-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA), have been proposed as biomarkers of the intake of these foods in humans. The pharmaco...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1978
ISSN: 0021-5198
DOI: 10.1254/jjp.28.41