Metabolism of isothiocyanates in individuals with positive and null GSTT1 and M1 genotypes after drinking watercress juice

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منابع مشابه

Metabolism of isothiocyanates in individuals with positive and null GSTT1 and M1 genotypes after drinking watercress juice.

BACKGROUND & AIMS Isothiocyanates (ITCs) derived from cruciferous vegetables have been shown to be promising agents against cancer in human cell culture, animal models, and in epidemiological studies. Several epidemiological studies have demonstrated an inverse relationship between intake of dietary isothiocyanates and the risk of cancers, particularly lung, colon, and breast. More importantly,...

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prevalence of null genotypes of glutathione s-transferase t1 (gstt1) and m1 (gstm1) in seven iranian populations

background: previous studies have revealed significant differences between populations for genotypic frequencies of glutathione s-transferase t1 ( gstt1 ) and m1 ( gstm1 ) polymorphisms. in order to find the frequency of the null genotypes of gstm1 and gstt1 in iranian populations, the present study was carried out. methods: the total study subjects consisted of 1340 unrelated healthy muslims/i...

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"frequency of glutathione s-transferase m1 (gstm1) and gstt1 null genotypes in fars population (south of iran)"

the genes glutathione s-transferase m1 (gstm1) and gstt1 code for cytosolic enzymes gstµ and gstθ, respectively, which are involved in phase ii metabolism. in human, both genes may be deleted. in the present study, the genetic polymorphisms of gstm1 and gstt1 were detected by pcr method in 236 healthy individuals from shiraz population, fars province, south of iran. the frequency of gstm1 and g...

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Prevalence of Null Genotypes of Glutathione S-Transferase T1 (GSTT1) and M1 (GSTM1) in Seven Iranian Populations

BACKGROUND Previous studies have revealed significant differences between populations for genotypic frequencies of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) polymorphisms. In order to find the frequency of the null genotypes of GSTM1 and GSTT1 in Iranian populations, the present study was carried out. METHODS The total study subjects consisted of 1340 unrelated healthy Muslims/Irani...

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ژورنال

عنوان ژورنال: Clinical Nutrition

سال: 2010

ISSN: 0261-5614

DOI: 10.1016/j.clnu.2010.06.010