Metabolism of 14C-Nomilin in Yuzu Fruit.

Metabolism of 14C-labelled alphaxalone in man.

The metabolism of 14C-labelled alphaxalone, dispensed as Althesin, was studied in normal patients, patients with obstructive jaundice and patients with chronic renal disease and anuria. The radioactive label was removed rapidly from the plasma following i.v. administration. The major portion of the label was excreted in the urine. In patients with normal renal function 14C-labelled alphaxalone ...

Cyclophosphamide-14C metabolism in the angora rabbit.

Mammary metabolism in lactating sows: arteriovenous differences of milk precursors and the mammary metabolism of [14C]glucose and [14C]acetate.

I. The following techniques, which have been applied successfully to goats, were used to study mammary metabolism in lactating sows : (I) measurements of mammary arteriovenous (A-V) differences in milk precursors in the conscious undisturbed animal (five sows); (2) continuous intravenous infusion of [U-14C]glucose with concomitant arterial and mammary venous blood sampling for measurement of ma...

Metabolism of [14C]spermidine and [14C]putrescine in normal volunteers and in cancer patients.

The administration of [14C]putrescine or [14C]spermidine (i.v., 100 muCi) to normal volunteers or patients with advanced cancer resulted in alpha-phase half-lives of 40 and 30 sec and beta-phase half-lives of 30 and 60 min, respectively. No significant differences were found between the plasma decay curves of normals and those of cancer patients. Urinary excretion was similar with both groups e...

Metabolism of D-cephaloglycin-14C and L-cephaloglycin-14C in the rat.

The fate of the orally effective antibiotic D-cephaloglycin and its much less active L-enantiomer has been studied in the rat. D-Cephaloglycin-14C is metabolized by two pathways, (1) hydrolysis of the amide linkage to form D-2-phenylglycine-14C and (2) deacetylation to form deacetyl-D-cephaloglycinUC. D-Cephaloglycin is absorbed from the gastro-intestinal tract at least in part as the intact an...