Metabolism and biochemical toxicity of PCBs and PBBs

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Metabolism and biochemical toxicity of PCBs and PBBs

One of the major biochemical effects of PCBs is the induction of microsomal enzymes in the liver. Risebrough et al. (1) suggested that PCBs have the capability to induce the activities of microsomal enzymes. Subsequently, Street et al. (2), demonstrated the induction of liver enzymes in rats by PCBs. Since then, a great number of articles have been published on this subject. The enzyme systems ...

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Chemistry of PCBs and PBBs

Introduction A recent book by Hutzinger et al. (1) reviews the chemistry of chlorinated biphenyls through the end of 1973. This wide-ranging review also includes discussions of metabolism and determination of chlorinated biphenyls. The present report reviews areas of chlorobiphenyl and bromobiphenyl chemistry held to be pertinent to the Subcommittee's concern for possible health effects of thes...

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Toxicity of polybrominated biphenyls (PBBs) in Domestic and laboratory animals.

The composition, environmental fate, and effects of the polybrominated biphenyls (Firemaster BP-6 or FF-1) involved in the accidental contamination of cattle feed in Michigan in 1973 are reviewed. Toxic effects referred to in this report are limited to those occurring in domestic and laboratory animals and include general toxicity, neurobehavioral toxicity, immunotoxicity, reproductive toxicity...

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بسیاری از پدیده ها در جهان ما اساساً غیرخطی هستند، و توسط معادلات غیرخطی ‎‏بیان شد‎‎‏ه اند. از آنجا که ظهور کامپیوترهای رقمی با عملکرد بالا، حل مسایل خطی را آسان تر می کند. با این حال، به طور کلی به دست آوردن جوابهای دقیق از مسایل غیرخطی دشوار است. روش عددی، به طور کلی محاسبه پیچیده مسایل غیرخطی را اداره می کند. با این حال، دادن نقاط به یک منحنی و به دست آوردن منحنی کامل که اغلب پرهزینه و ...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1978

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.7824147