Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New insights into chitosan-DNA interactions using isothermal titration microcalorimetry.

The interaction of chitosan with plasmid DNA was investigated as a function of pH, buffer composition, degree of deacetylation (DDA), and molecular weight (M(n)) of chitosan, using isothermal titration microcalorimetry (ITC). The Single Set of Identical Sites model was used to obtain the enthalpy of interaction, the binding constant, and the stoichiometry of binding. The chitosan-DNA interactio...

متن کامل

Standards in Isothermal Microcalorimetry

The main calorimetric principles used in isothermal microcalorimetry are briefly discussed. Different chemical calibration and test reactions are discussed, with a focus on reactions suitable for ambient conditions: reactions initiated by mixing of liquids (including titration microcalorimetry), dissolution of solid compounds and of slightly soluble gases, a photochemical process, and thermal p...

متن کامل

Bacteriostatic or bactericidal effect of linezolid against multiresistant Streptococcus pneumoniae.

The nasopharynx plays a critical role as the reservoir of Streptococcus pneumoniae, including drug-resistant strains particularly in children attending day care centers. A total 58 nasopharyngeal, multiresistant isolates of S. pneumoniae collected from healthy pre-school children were susceptible to linezolid (MIC = 0.25-1 mg/l), irrespective of serotype and drug resistance pattern. The majorit...

متن کامل

Isothermal microcalorimetry in applied biology

Techniques of isothermal microcalorimetry have been much improved during the past two decades. In addition to their use in fundamental research, applications of practical importance have been established in some areas. However, no significant use of isothermal microcalorimetry has yet been seen in practical applications of biology, despite many methodological studies reported from that area. Th...

متن کامل

Bactericidal versus Bacteriostatic Antibiotic Therapy

/Ag/ml; strain2-MIC 1 ,g/ml, MBC 2 ,g/ml. Animals were treated with either ampicillin or chloramphenicol in dosages that achieved a peak bactericidal effect in cerebrospinal fluid (CSF) for ampicillin against both strains. Two different dosages were used for chloramphenicol. The first dosage achieved a peak CSF concentration of 4.4±1.1 gg/ml that produced a bacteriostatic effect against strainI...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Visualized Experiments

سال: 2020

ISSN: 1940-087X

DOI: 10.3791/61703