Metabolic effects of androgen deprivation therapy
نویسندگان
چکیده
منابع مشابه
Metabolic effects of androgen deprivation therapy
The therapeutic effects and side effects of androgen deprivation therapy (ADT), which is a main treatment method for metastatic prostate cancer, are well known, but the metabolic effects have only recently been studied. This review describes the effects of ADT on body habitus, insulin resistance, lipid profiles, diabetes, metabolic syndrome, and cardiovascular morbidity and mortality. The revie...
متن کاملAndrogen deprivation therapy.
© TouCh MEdiCal MEdia 2014 This review describes strategies for producing castrate levels of testosterone in men with androgen-sensitive prostate cancer (PC) and the associated toxicities, with particular focus on the re-emergence and potential benefits of parenteral estrogen. In the developed world, PC is the commonest malignancy and second commonest cause of cancer death affecting men. Its in...
متن کاملAndrogen deprivation therapy through bilateral orchiectomy: increased metabolic risks.
Prostate cancer is one of the most common malignancies in men. Previous research has determined that androgen deprivation therapy (ADT) may be accompanied by an unfavourable metabolic profile. In this prospective study, 133 men were recruited, including 46 prostate cancer patients who had undergone bilateral orchiectomy and been on flutamide (the ADT group), 37 men with prostate cancer who had ...
متن کاملAndrogen deprivation therapy complications.
Androgen deprivation therapy (ADT) is increasingly used to treat advanced prostate cancer and is also utilised as adjuvant or neo-adjuvant treatment for high-risk disease. The resulting suppression of endogenous testosterone production has deleterious effects on quality of life, including hot flushes, reduced mood and cognition and diminished sexual function. Cross-sectional and longitudinal st...
متن کاملAdverse effects of androgen deprivation therapy in patients with prostate cancer: focus on metabolic complications.
Prostate cancer is the most common cancer among men and androgen deprivation therapy (ADT) is the most effective treatment for this disease. The cornerstone of the treatment of prostate cancer is inhibition of testosterone production which interrupts testosterone-induced growth of the prostate tumor. The dramatic decrease in testosterone levels, however, has several undesirable effects on the m...
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ژورنال
عنوان ژورنال: Korean Journal of Urology
سال: 2015
ISSN: 2005-6737,2005-6745
DOI: 10.4111/kju.2015.56.1.12