METABOLIC ALTERATIONS FOLLOWING THERMAL BURNS

Alterations in neuromuscular function following thermal injury.

Severe burn injury can result in dramatic changes in human physiology and biochemistry. Aberrant responses, hypersensitivity and potentially lethal hyperkalemia to depolarising [1,2] and hyposensitivity to non-depolarising [2,3] muscle relaxants have been noted in burn trauma. The molecular basis of these responses is currently thought to be due to an increase in nicotinic acetylcholine recepto...

Experimental thermal burns.

Metabolic acidosis in burns.

All our tests with the Navictda sp. were negative. It was apparent, therefore, that this was not the cause of trouble but that Fragilaria striatula was suspect. This is in agreement with the report of Fraser and Lyell (1963) that an eczematous eruption in an Aberdeen fisherman was caused by Fragilaria struia. That this diatom, alone out of so many present in the sea, should have a harmful effec...

Airbag-Induced Thermal Skin Burns

Two new techniques for investigating the thermal skinburn potential of airbags are presented. A reduced-volume airbag test procedure has been developed to obtain airbag pressures that are representative of a dynamic ridedown event during a static deployment. Temperature and heat flux measurements made with this procedure can be used to predict airbag thermal burn potential. Measurements from th...

Alterations in skeletal and mineral metabolism following thermal injuries.

Severe burns and other chronic inflammatory diseases are associated with altered skeletal metabolism that result in an increased incidence of osteopenia. In thermally injured children and adults there is a dramatic decrease in bone formation accompanied with an increase or maintenance of bone resorption. Children also exhibit a growth delay and subsequently fail to reach a predicted stature. An...