Meta-analysis: IL-28B genotype and sustained viral clearance in HCV genotype 1 patients
نویسندگان
چکیده
منابع مشابه
Meta-analysis: IL-28B genotype and sustained viral clearance in HCV genotype 1 patients.
BACKGROUND Polymorphisms in the IL-28B region are a strong predictor of sustained virologic response (SVR) in individual studies of HCV genotype 1 patients receiving peginterferon (pegIFN) and ribavirin. AIM To obtain a pooled odds ratio (OR) of SVR in patients of varying race with the favourable IL-28B genotype compared to those with the unfavourable genotype. METHODS A literature search w...
متن کاملPolymorphism of IL-28B Gene (rs12979860) in HCV Genotype 1 Patients Treated by Pegylated Interferon and Ribavirin
Background: Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue mostly due to the interleukin 28B (IL-28B) polymorphism effects in chronic HCV patients. The aim of this study was to detect the polymorphism of IL-28B gene (rs12979860) in HCV genotype 1 patients treated with pegylated Interferon and Ribavirin. Methods...
متن کاملPredictability of IL-28B-polymorphism on protease-inhibitor-based triple-therapy in chronic HCV-genotype-1 patients: A meta-analysis.
AIM To investigate the predictability of interleukin-28B single nucleotide polymorphism rs12979860 with respect to sustained virological response (SVR) in chronically hepatitis C virus (HCV) genotype-1 patients treated with a protease-inhibitor and pegylated interferon-α (Peg-INF-α) based triple-therapy. METHODS We searched PubMed, the Cochrane Library and Web of Knowledge for studies regardi...
متن کاملpolymorphism of il-28b gene (rs12979860) in hcv genotype 1 patients treated by pegylated interferon and ribavirin
background: nowadays, the immune response to hepatitis c (hcv) treatment has become a crucial issue mostly due to the interleukin 28b (il-28b) polymorphism effects in chronic hcv patients. the aim of this study was to detect the polymorphism of il-28b gene (rs12979860) in hcv genotype 1 patients treated with pegylated interferon and ribavirin. methods: from the 2010 to 2012, a total of 115 peri...
متن کاملPolymorphism of IL-28B Gene (rs12979860) in HCV Genotype 1Patients Treated by Pegylated Interferon and Ribavirin.
BACKGROUND Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue mostly due to the interleukin 28B (IL-28B) polymorphism effects in chronic HCV patients. The aim of this study was to detect the polymorphism of IL-28B gene (rs12979860) in HCV genotype 1 patients treated with pegylated Interferon and Ribavirin. METHODS From the 2010 to 2012, a total of 115 peri...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2012
ISSN: 0269-2813
DOI: 10.1111/j.1365-2036.2012.05145.x