Meta-analysis for pathway enrichment analysis when combining multiple genomic studies

META-ANALYSIS FOR PATHWAY ENRICHMENT ANALYSIS AND BIOMARKER DETECTION WHEN COMBINING MULTIPLE GENOMIC STUDIES by

Meta-analysis for pathway enrichment analysis when combining multiple genomic studies

MOTIVATION Many pathway analysis (or gene set enrichment analysis) methods have been developed to identify enriched pathways under different biological states within a genomic study. As more and more microarray datasets accumulate, meta-analysis methods have also been developed to integrate information among multiple studies. Currently, most meta-analysis methods for combining genomic studies f...

Meta-Analysis of Pathway Enrichment: Combining Independent and Dependent Omics Data Sets

A major challenge in current systems biology is the combination and integrative analysis of large data sets obtained from different high-throughput omics platforms, such as mass spectrometry based Metabolomics and Proteomics or DNA microarray or RNA-seq-based Transcriptomics. Especially in the case of non-targeted Metabolomics experiments, where it is often impossible to unambiguously map ion f...

Meta-Analysis of Theft Studies in Iran

Theft is one of the crucial criminal practices that threaten the public and social security of the community, and its prevalence is a clear indication of social insecurity. This study aimed to assess the prevalence of the theft at its all levels and aspects by using systematic review and meta-analysis. The statistical population of this synthesizing study includes all of the research studies in...

Meta-analysis of suicide studies in Iran

Introduction: The purpose of this study is to investigate the meta-analysis of published articles on the factors affecting suicide. Method: From 15 selected studies, appropriate statistics were recorded to calculate the effect size and other required information and with CMA2 software, the effect size was calculated and hypotheses were analyzed. Findings: The results of the present study sh...