MEMBRANE-PERMEABILITY ASSAY USING CACO-2 CELLS IN DRUG DISCOVERY
نویسندگان
چکیده
منابع مشابه
Caco-2 Cell Lines in Drug Discovery- an Updated Perspective
Cell lines are the invitro models used for the drug permeability studies in the preclinical and clinical phases of the drug discovery. Cell line models are simple and quick to use and avoids the usage of animal models for pharmacological and toxicological studies and hence cost effective, produce reliable and reproducible results for understanding and evaluating the permeability characteristics...
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ژورنال
عنوان ژورنال: Drug Metabolism and Pharmacokinetics
سال: 2001
ISSN: 0916-1139
DOI: 10.2133/dmpk.16.supplement_152