Memantine-induced sustained unconsciousness
نویسندگان
چکیده
منابع مشابه
Top-down mechanisms of anesthetic-induced unconsciousness
The question of how structurally and pharmacologically diverse general anesthetics disrupt consciousness has persisted since the nineteenth century. There has traditionally been a significant focus on "bottom-up" mechanisms of anesthetic action, in terms of sensory processing, arousal systems, and structural scales. However, recent evidence suggests that the neural mechanisms of anesthetic-indu...
متن کاملNeurophysiological correlates of sevoflurane-induced unconsciousness.
BACKGROUND Recent studies of anesthetic-induced unconsciousness in humans have focused predominantly on the intravenous drug propofol and have identified anterior dominance of alpha rhythms and frontal phase-amplitude coupling patterns as neurophysiological markers. However, it is unclear whether the correlates of propofol-induced unconsciousness are generalizable to inhaled anesthetics, which ...
متن کاملReconfiguration of network hub structure after propofol-induced unconsciousness.
INTRODUCTION General anesthesia induces unconsciousness along with functional changes in brain networks. Considering the essential role of hub structures for efficient information transmission, the authors hypothesized that anesthetics have an effect on the hub structure of functional brain networks. METHODS Graph theoretical network analysis was carried out to study the network properties of...
متن کاملUnresponsiveness ≠ unconsciousness.
Consciousness is subjective experience. During both sleep and anesthesia, consciousness is common, evidenced by dreaming. A defining feature of dreaming is that, while conscious, we do not experience our environment; we are disconnected. Besides inducing behavioral unresponsiveness, a key goal of anesthesia is to prevent the experience of surgery (connected consciousness), by inducing either un...
متن کاملA transition in brain state during propofol-induced unconsciousness.
Rhythmic oscillations shape cortical dynamics during active behavior, sleep, and general anesthesia. Cross-frequency phase-amplitude coupling is a prominent feature of cortical oscillations, but its role in organizing conscious and unconscious brain states is poorly understood. Using high-density EEG and intracranial electrocorticography during gradual induction of propofol general anesthesia i...
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ژورنال
عنوان ژورنال: Neurology and Clinical Neuroscience
سال: 2016
ISSN: 2049-4173
DOI: 10.1111/ncn3.12076