Melt Spinning of Poly (vinyl alcohol).

Evaluation of morphology and cell behaviour of a novel synthesized electrospun poly(vinyl pyrrolidone)/poly(vinyl alcohol)/hydroxyapatite nanofibers

Objective(s): Three-dimensional structures such as nanofibrous scaffolds are being used in biomedical engineering as well as provide a site for cells to attach and proliferate leading to tissue formation. In the present study, poly(vinyl pyrrolidone) (PVP)/ poly(vinyl alcohol)(PVA) hybrid nanofibrous scaffold was synthesized by electrospinning. Materials and Methods: The effect of adding nano h...

Synthesis of pH Sensitive Hydrogels Based on Poly Vinyl Alcohol and Poly Acrylic Acid

     In this research, hydrogels based on poly vinyl alcohol and poly acrylic acid blend were prepared which were cross-linked by applied thermal conditions. Afterward, effects of time and heating on water uptake were investigated. The highest water uptake value exhibited by the sample that was heated for 20 min. at 110 ºC was about 2129% after 4 days at equilibrium state. Hydrogels exhibited p...

Solid state solubility of miconazole in poly[(ethylene glycol)-g-vinyl alcohol] using hot-melt extrusion.

The use of hot-melt extrusion for preparing homogeneous API-excipient mixtures is studied for miconazole-PEG-g-PVA [poly(ethylene glycol)-poly(vinyl alcohol) graft copolymer] solid dispersions with a 5 cm(3) table-top, twin-screw corotating microcompounder (DSM Xplore). Phase behavior of PEG-g-PVA, miscibility of miconazole in PEG-g-PVA and the partitioning of miconazole between PEG and PVA amo...

Biological Properties of Blend Nanofibrous Scaffolds from Poly(caprolactone)-Chitosan-Poly(vinyl alcohol)

Intramolecular crosslinking of poly(vinyl alcohol)

Poly(vinyl alcohol) is crosslinked in dilute solution (c = 0.1 wt%) with glutaraldehyde. The reaction product is characterized by viscometry and gel permeation chromatography (g.p.c.). The intrinsic viscosity decreases with increasing degree of crosslinking and does not depend on temperature. G.p.c. reveals that the reaction product is not homogeneous, but consists of a mixture of particles wit...