Meiosis: Checking Chromosomes Pair up Properly

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Meiosis: Checking Chromosomes Pair up Properly

Faithful recombination and chromosome segregation in meiosis require regulated steps of homolog recognition and association which are monitored by meiotic checkpoints. A recent study in the nematode Caenorhabditis elegans has identified a checkpoint mechanism that monitors chromosome pairing during meiosis.

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The Origin of Iso-Chromosomes at Meiosis.

N 1.50-CHROMOSOME is a chromosome having two identical arms A (DARLINGTON 1939). Such chromosomes have been studied recently by RHOADES (1940) in Zea and by DARLINGTON (1940) in Fritillaria. It is also very probable that the extra chromosomes in secondary trisomics, such as the numerous types which have been found in Datura (BLAKESLEE and AVERY 1938) are true iso-chromosomes. The manner in whic...

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The Chromosomes of Birds during Meiosis.

The cytological analysis of meiotic chromosomes is an exceptional tool to approach complex processes such as synapsis and recombination during the division. Chromosome studies of meiosis have been especially valuable in birds, where naturally occurring mutants or experimental knock-out animals are not available to fully investigate the basic mechanisms of major meiotic events. This review highl...

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Centromere pairing – tethering partner chromosomes in meiosis I

In meiosis, homologous chromosomes face the obstacle of finding, holding onto and segregating away from their partner chromosome. There is increasing evidence, in a diverse range of organisms, that centromere-centromere interactions that occur in late prophase are an important mechanism in ensuring segregation fidelity. Centromere pairing appears to initiate when homologous chromosomes synapse ...

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Thymidine-H(3) of high specific activity was used to study the distribution of labeled chromatids during meiotic divisions in spermatocytes of a species of grasshopper (Orthoptera). The distribution is regularly semiconservative as has been shown previously for mitosis, i.e., all chromatids are labeled after incorporation of thymidine-H(3) into DNA at premeiotic interphase. If incorporation occ...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2006

ISSN: 0960-9822

DOI: 10.1016/j.cub.2006.03.002